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实验室纯化水和注射用水系统怎么消毒?

来源:http://www.sdrunjing.com/ 日期:2020-05-05 发布人:润静小编
  实验室纯化水系统和注射用水系统,用紫外线定期消毒等是否就可以了?若不行,应该用什么方法?
  Is it OK to disinfect the laboratory purified water system and injection water system with UV regularly? If not, what method should be used?
  《药品生产质量管理规范(2010年修订)》要求企业应对纯化水、注射用水管道进行清洗消毒,而没有强制要求消毒的方式方法。紫外线消毒效果的影响因素较多,如紫外线波长、强度、照射时间、水层厚度等,不易控制,可作为消毒的辅助手段。
  Pharmaceutical production quality management standard (revised in 2010) requires enterprises to clean and disinfect the purified water and injection water pipes, but there is no compulsory disinfection method. There are many factors affecting the efficacy of UV disinfection, such as UV wavelength, intensity, irradiation time, water layer thickness, etc., which are not easy to control and can be used as auxiliary means of disinfection.
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  纯化水系统和注射用水的消毒有多重方式,例如:纯化水系统可采用巴氏消毒或纯蒸汽灭菌,注射用水可采用纯蒸汽灭菌或过热水灭菌等。而紫外线仅仅是辅助的方式,可以延长消毒周期,但其效果十分有限。
  There are multiple ways to disinfect purified water system and water for injection, such as pasteurization or pure steam sterilization for purified water system, pure steam sterilization or superheated water sterilization for water for injection, etc. Ultraviolet is only an auxiliary way, which can prolong the sterilization cycle, but its effect is very limited.
  企业可以根据自身的设备情况以及消毒周期来确定具体的消毒和灭菌方式,并对其进行充分的验证。但一般情况下,不建议纯化水系统和注射用水系统仅仅采用紫外线定期消毒这一种方式。
  Enterprises can determine specific disinfection and sterilization methods according to their own equipment conditions and disinfection cycle, and fully verify them. However, in general, it is not recommended that the purified water system and the water for injection system should only be sterilized by ultraviolet regularly.

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